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Publications

  1. Wu, B., Chang, J.H., Singh, P., Hostetler, A., Xiang, Y., Guo, S., Wang, F., Zhong, J., Leifer, B., Choudhary, A., Westcott, P., Koehler, A. Small Molecule Modulators of TOX protein to Re-invigorate T cell Activity. bioRxiv. https://doi.org/10.1101/2025.03.03.641115

  2. Owumi, S., Olanlokun, J. O., Wu, B., Duro-Ladipo, A. M., Oyelere, S. E., Khan, S. I., & Oyelere, A. K. (2024). Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models. Molecules, 29(23), 5658. DOI: 10.3390/molecules29235658.

  3. Kohrt, S. E., Novak, E. J., Tapadar, S., Wu, B., Strope, J., Asante, Y., Kim, H., Chang, M. S., Gurdak, D., Khalil, A., Rood, M., Raftery, E., Stavreva, D., Nguyen, H. M., Brown, L. G., Ramser, M., Peer, C., Meyers, W. M., Aboreden, N., Gryder, B. E. (2024). Small-molecule disruption of androgen receptor–dependent chromatin clusters. Proceedings of the National Academy of Sciences, 121(48), e2406239121. DOI: 10.1073/pnas.2406239121.

  4. Wu, B., Koehler, AN., Westcott, PM. New opportunities to overcome T cell dysfunction: the role of transcription factors and how to target them. Trends in Biochemical Sciences. Volume 49, Issue 11. p1014-1029. DOI: 10.1016/j.tibs.2024.08.002.

  5. Wu, B., Tapadar S, Ruan Z, Sun CQ, Arnold RS, Johnston A, Olugbami JO, Arunsi U, Gaul DA, Petros JA, Kobayashi T. A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective Against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy. ACS Pharmacology & Translational Science. 2024 Sep 5;7(10):3155-69. DOI: 10.1021/acsptsci.4c00358.

  6. Chandrasekaran, B., Tapadar, S.  Wu, B., Tyagi. A., Saran. Uttara., Johnson. A., Gaul D., Oyelere. A.K., Damodaran. C. Antiandrogen Equipped Histone Deacetylase Inhibitors selectively inhibits Androgen Receptor (AR) and AR-Variant 7 (AR-V7) in Castration- Resistant Prostate Cancer (CRPC) Cancers MDPI. 2023, 15(6), 1769; DOI: 10.3390/cancers15061769.

  7. Owumi, S. E., Kazeem, A. I., Wu, B., Ishokare, L. O., Arunsi, U. O., & Oyelere, A. K. (2022). Apigeninidin-rich Sorghum bicolor (L. Moench) extracts suppress A549 cells proliferation and ameliorate toxicity of aflatoxin B1-mediated liver and kidney derangement in rats. Scientific Reports, 12(1), 1-19. 2022. DOI: 10.1038/s41598-022-10926-1.

  8. Wu, B., Sodji, Q. H., Oyelere, A. K. Inflammation, Fibrosis and Cancer: Mechanisms, Therapeutic Options and Challenges. Cancers MDPI 2022, 14, 3; DOI:10.3390/cancers14030552.

  9. Faura, G. G.*, Wu, B.*, Oyelere, A. K., & France, S. Synthetic Methodology-Enabled Discovery of a Tunable Indole Template for COX-1 Inhibition and Anti-cancer activity. Bioorganic & Medicinal Chemistry. 2022 116633. DOI: 10.1016/j.bmc.2022.116633.

  10. Wu, B., Payero, B., Taylor, S., Oyelere, A. K. Discovery of novel STAT3 DNA binding domain inhibitors. Fut. Med. Chem. 2021 13(15), 1253-1269.  DOI:10.4155/fmc-2021-0088.

  11. Wu, B. Discovery of novel drugs with tissue and cell-type selectivity for cancer and inflammation. (Doctoral dissertation, Georgia Institute of Technology). 2021.

  12. Tapadar, S.; Fathi, S.; Wu, B.; Sun, C.Q.; Raji, I.; Moore, S.G.; Arnold, R.S.; Gaul, D.A.; Petros, J.A.; Oyelere, A.K. Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents. Cancers 2020, 12, 3095; DOI: 10.3390/cancers12113095.

  13. Caggia, S., Tapadar, S., Garrett, A., Wu, B., Venugopal, S. V., Garrett, A. S., Kumar, A., Stiffend, J. S., Davis, J. S., Oyelere, A. K., Khan, S. A. Small molecule inhibitors targeting Gαi2 protein attenuate migration of cancer cells. Cancers 2020, 12, 1631; DOI:10.3390/cancers12061631.

  14. Wu, B., Fathi, S., Mortley, S., Mohiuddin, M., Jang, Y. C., Oyelere, A. K. Pyrimethamine conjugated histone deacetylase inhibitors: design, synthesis and evidence for triple negative breast cancer selective cytotoxicity. Bioorg. Med. Chem. 2020, 28, 115345; DOI: 10.1016/j.bmc.2020.115345.

  15. Crooke, S. N., Schimer, J., Raji, I., Wu, B., Oyelere, A. K., Finn, M. G. Lung Tissue Delivery of Virus-Like Particles Mediated by Macrolide Antibiotics. Mol. Pharm. 2019, 16, 2947-2955. DOI: 10.1021/acs.molpharmaceut.9b00180.

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